`` DNA computer that can calculate square root up to 900 using DNA '' is developed


by

iLexx

DNA computing and is composed of four bases deoxyribonucleic acid (DNA) of performing calculations in a test tube using a completely different mechanism from the electronic device computer is. A research team at the University of Rochester in the United States reported that it has developed a DNA computer that can calculate square roots up to 900.

Programmable DNA Nanoindicator-Based Platform for Large-Scale Square Root Logic Biocomputing-Zhou-2019-Small-Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201903489

A computer made from DNA can compute the square root of 900 | New Scientist
https://www.newscientist.com/article/2228461-a-computer-made-from-dna-can-compute-the-square-root-of-900/

Test tube DNA computer calculates the square root of 900 | ZDNet
https://www.zdnet.com/article/test-tube-dna-computer-calculates-the-square-root-of-900/

A DNA-Based Computer Calculates Square Roots Up To 900 | Hackaday
https://hackaday.com/2020/01/12/a-dna-based-computer-calculates-square-roots-up-to-900/



The DNA computer, bases adenine constituting the DNA (A) and thymine (T), and complementary binding of a combination of guanine (G) and cytosine (C) to form a complex,

hybridization with Computer. The first computer to invent the DNA computer was American computer scientist Leonard Edelman .

Edelman noticed the similarity between computer and DNA while reading `` Molecular Biology of Genes ' ', and in 1994 a paper titled `` Molecular computation of solutions to combinatorial problems '' Announced. The idea of DNA computers has come to be known to the world.

Research on DNA computers has continued since then, but even more than 20 years after the first paper, complex mathematical operations could not be realized with DNA computers. For example, calculating a square root requires a 10-bit logic circuit that can process a 4-bit binary number, but the existing DNA computer system could not demonstrate that much processing power.


by

monkeybusiness

Meanwhile, the research team of Professor Chunlei Guo of the University of Rochester reported that he has developed a DNA computer that can store and process information using 32 DNA strands. 'We designed the DNA sequence and programmed the DNA strand displacement reaction to achieve square root calculations up to 900,' Guo says.

The DNA computer devised by Guo's research team first encodes up to 900 numerical values in DNA and associates the color of the fluorescent marker with each numerical value. Then, when the calculation of the square root is processed through a logic gate , the overall fluorescent signal is changed according to the original number, and the calculation result seems to be output as a color.

In recent years, when Moore's law is breaking down, the development of DNA computers that are more than 10 times smaller than existing transistors is expected to develop in the future. 'DNA computers are still in their infancy, but they have great potential in solving problems that today's silicon-based computers can't handle,' Guo said.


by Vladdeep

in Science, Posted by log1h_ik