Zinc and folic acid supplements turned out to be `` no effect to increase sperm '', on the contrary there is also the possibility of side effects



Zinc is taken as a `` supplement that improves the quantity and quality of semen '' along with folic acid , which is thought to be closely related to active cell division, because zinc deficiency causes male gonadal dysfunction and reduced spermatogenesis Has been done. However, a detailed analysis of semen from more than 2,000 men revealed that zinc and folic acid supplements do not have the effect of improving semen quantity or quality.

Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network

Male infertility got no boost from zinc, folic acid in study

Zinc, folic acid supplements fail to enhance male fertility | EurekAlert! Science News

Taking folic acid and zinc supplements to boost male fertility has NO effect | Daily Mail Online

One third of couples suffering from infertility have been attributed to male infertility , in which case the quality of male semen is a major issue. Therefore, it has been thought that fertility is improved by actively ingesting zinc contained in semen at a concentration 30 times that of blood to improve semen quality.



However, whether zinc and folic acid supplements actually enhance semen quality has not been extensively tested, and a study by the National Institutes of Health internal research program senior researcher Enrique Schisterman et al. The team conducted an experiment in which men were actually drinking supplements, and verified the effect.

The research team first recruited 2,370 men working on fertility with their partners at a healthcare facility as participants in the experiment and divided them into two groups of 1185. Then, in the experimental group asked to take a supplicant that contains zinc 30mg and folic acid 5mg one tablet a day, and the other one of the control group placebo get to drink a placebo-controlled trial was conducted six months.

At the end of the experimental period, the researchers looked at pregnancy rates in both groups, and found that men in the experimental group had a 34% chance of giving birth, compared with 35% in the control group, rather than taking placebo. The result is that the probability is slightly higher for the group. Furthermore, when examining the 'percentage of sperm DNA fragmentation', which is one of the causes of infertility, it was 29.7% in the experimental group, but 27.2% in the control group. Gave the opposite result.

The research team compared the quality of the semen in both groups in detail, such as 'concentration and amount, total number of sperm, motility, shape', but no significant difference was found. It was also found that men in the experimental group reported more gastrointestinal disorders, such as abdominal pain or abdominal discomfort, nausea, and vomiting, than did men in the control group.

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'People undergoing fertility treatment are looking for a way to treat the matter, and the cost of supplements is $ 60 per month, and tens of thousands of dollars (several hundreds),' said Schisterman. Is cheaper than such invasive treatment, but the experimental results were disappointing. '

`` In large and rigorous randomized trials, dietary supplements such as zinc and folic acid do not increase the chances of a couple becoming pregnant, but rather cause adverse side effects, '' said co-author Matthew Peterson. For men of all ages, a healthy diet can help maintain reproductive function, but if you take additional specialties to improve semen quality, It doesn't make sense, 'he said, adding that supplements are ineffective in treating fertility.

in Note, Posted by log1l_ks