Quality sleep can help reduce the risk of Alzheimer's disease


by

Tracey Hocking

It was found that brain waves generated during deep sleep (non-REM sleep) promoted an increase in cerebrospinal fluid flow and washed away toxins that are thought to cause Alzheimer's disease and other diseases.

Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep | Science
https://science.sciencemag.org/content/366/6465/628



Sleep And Alzheimer's: Cerebrospinal Fluid Washes Away Toxins: Shots-Health News: NPR

https://www.npr.org/sections/health-shots/2019/10/31/775068218/how-deep-sleep-may-help-the-brain-clear-alzheimers-toxins

This was clarified by research by Assistant Professor Laura Lewis at Boston University, and the paper was published in Science.

As for the relationship between Alzheimer's disease and sleep, it has been known that 'Alzheimer's disease patients often have problems with sleep' and 'Persons with sleep disorders are prone to Alzheimer's disease'.

Associate Professor Lewis and his colleagues focused on “brain health and sleep” investigated what happens in the brain when sleeping. Already, research on animals in 2013 found that cerebrospinal fluid flow increased during sleep and removed toxins and other wastes related to Alzheimer's disease. Confirmed in real time that this movement also occurs in the human brain.


by DANNY G

It was also found that cerebrospinal fluid flow occurred several seconds after the “slow wave” (slow wave) occurred in the neuron. The cycle was about once every 20 seconds. Slow waves appear when it comes to non-REM sleep, and Alzheimer's patients are known to have less slow waves. This suggests that the slow wave decrease reduces the “intracerebral lavage cycle”, leading to a reduction in toxin removal capacity.

Lewis also discovered that blood flow in the brain decreases as cerebrospinal fluid flow increases. This indicates that there is a lot of room for cerebrospinal fluid to carry waste.

`` Ensuring quality sleep helps reduce the risk of Alzheimer's disease, '' says William Jagast, University of California, Berkeley, who studies the relationship between NREM sleep and beta-amyloid that accumulates in the brain of Alzheimer's disease patients. And comments.

According to Professor Jagast, the results of this study are in good agreement with other studies on sleep and Alzheimer's disease. It is possible that the amyloid is in a vicious circle where the quality of sleep is reduced, thereby increasing amyloid and reducing waste removal.

in Science, Posted by logc_nt