The possibility of `` drinking alcohol when the brain is small '' is indicated instead of `` alcohol brain atrophy ''



Past studies have often shown that there is a relationship between drinking alcohol and brain atrophy. However, a new study suggests that instead of `` drinking the brain, the brain will atrophy '', instead of `` drinking alcohol because the part of the brain is small '', a reverse causal relationship to the past It has been.

Convergent evidence for predispositional effects of brain gray matter volume on alcohol consumption-Biological Psychiatry

Which came first: Brain size or drinking propensity?

Associate Professor Ryan Bogdan, director of the Brain Lab at the University of Washington, who studies psychology and neurology, analyzed three different studies using images from brain scans. The three studies include a comparison of twins' drinking habits, long-term brain observations since childhood without alcohol consumption, and analysis of gene expression in postmortem brain tissue.

`` Our study provides some relevant evidence that there is a genetic component that causes both low gray matter and alcohol consumption, '' said lead author David Barranger. 'This finding does not rule out the hypothesis that alcohol abuse reduces gray matter, but suggests that brain volume was low from the beginning. It can be used as a “biological marker for genetic mutations associated with the tendency to become susceptible”. '


Adam Jaime

Analyzing three studies, they found that the amount of gray matter in two parts of the brain, the dorsolateral prefrontal cortex and the islet cortex, was linked to alcohol consumption. These parts are involved in emotions, memories, rewards, cognitive control, and decision making. Analysis of brain scan images from childhood who did not drink alcohol to adult drinking alcohol showed that there is a decrease in gene-related gray matter at these sites, indicating future alcohol consumption, In other words, it became a predictor of starting drinking when you were young.

Comparing brain scans of twins with different drinking habits, it was shown that twins who drink more often have less gray matter than twins who drink less. Interestingly, even though one of the twins was a heavy drinker, both showed low levels of gray matter. Researchers believe that low gray matter is not a result of alcohol consumption, but a vulnerability associated with alcohol consumption.

In addition, a study of gene expression data in the human brain showed that the genetic risk of alcohol consumption was more associated with gene expression in the dorsolateral prefrontal cortex than in other parts of the brain. From these, the researchers conclude that low prefrontal cortical gray matter may be posed by a genetic risk of alcohol consumption.

by thom masat

According to researchers, `` along with the findings that alcohol consumption causes gray matter loss, our data show that low levels of genetic gray matter at specific sites may promote alcohol consumption from a young age. This can accelerate the atrophy of the brain in certain or other areas. '

in Science, Posted by logq_fa