Researchers succeed in restoring brain function in pigs 4 hours after death
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The brains of mammals, including humans, are vulnerable to cessation of blood flow and decreased oxygen levels, and when the supply of oxygen and blood is cut off, consciousness and electrical activity of the brain disappear in a few seconds, and cell activity also It will take a few seconds to a few minutes. However, researchers at Yale University report that they observed the resumption of cell activity that should have stopped in the brain of pigs four hours after death.
Scientists restore some functions in a pig's brain hours after death | YaleNews
https://news.yale.edu/2019/04/17/scientists-restore-some-functions-pigs-brain-hours-after-death
Restoration of brain circulation and cellular functions hours post-mortem | Nature
4 hours after death, observation of cell activity = in the brain of an edible pig-Yale University: Jiji.com
https://www.jiji.com/jc/article?k=2019041800079&g=int
The death of cells in the brain, or 'death of the brain,' has been thought to be a rapid and irreversible event that occurs within a matter of seconds to minutes when the supply of oxygen and blood is cut off. .. However, in the laboratory of Nenad Sestan, a professor of neuroscience at Yale University, a small tissue sample may show viability even in cells several hours after death, so the complete brain of a pig was used as a sample. We conducted a survey on cell activity.
by Kameron Kincade
Professor Sestan and his colleagues connected a system called Brain Ex that circulates a unique solution to the vascular system of the pig's brain four hours after death. Then, the integrity of the nerve cells was maintained, and the functionality of specific nerve cells, glial cells, and vascular cells was restored.
According to Stefano G. Daniel, who was involved in the research, most of the research on the brain has used a small amount of tissue sample taken from the brain, and even if the brain was used, the function stopped. With this discovery, he says that he will be able to examine the original brain in the future, and will be able to proceed with research on the integrated action and connection of cells.
However, it should be noted that the purpose of this research is not 'restoration of consciousness'. On the other hand, the research team was preparing to stop the electrical activity of the brain by anesthesia or temperature decrease in case there were signs of recovery of consciousness.
Also, since the solution used in Brain Ex lacks many of the components originally contained in human blood, it is unclear whether the same method can be used for the human brain.
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