Proteins are discovered that can reduce one-third of the fat in the body in 18 days

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Mouse who performed treatment using natural protein "FGFBP 3" for 18 days succeeded in reducing one-third of fat in the body and said that the cancer center "Georgetown Lombardi Comprehensive Cancer Center" located in Georgetown, USA The research team of Anton Wellstein et al. Announced.

Fibroblast Growth Factor Binding Protein 3 (FGFBP 3) impacts carbohydrate and lipid metabolism | Scientific Reports
https://www.nature.com/articles/s41598-018-34238-5

Obese mice lose a third of their fat using a natural protein - ScienceDaily
https://www.sciencedaily.com/releases/2018/10/181029084038.htm

Researchers have succeeded in removing obesity-related disorders such as hyperglycemia from the mouse by a new therapy. It also helped to remove fat from fatty liver. Even though microscopic examination or clinical examination was done, it is said that side effects did not appear in the mouse.

FGFBP3 is a binding protein (BP), which is one of fibroblast growth factors (FGF), present in various living organisms from caterpillars to humans, and includes a wide range of "repair of wounds" and "control of cell growth" It is related to biological processes. It has also been reported that some FGFs act like hormones.

BP1, BP2, PB3 are proteins called chaperones that bind to FGF and are active in various parts of the body. Since BP1 increases in several cancers, it is thought that "the growth of certain cancer cells is related to the oversupply of FGF." Mr. Wellstein has been studying the gene of BP1 for a long time, and then researchers have started to do research on BP3.

And researchers discovered that the binding of chaperones to three proteins, FGF19, FGF21 and FGF23, is involved in metabolic control. The signals of FGF 19 and FGF 21 controlled the storage and use of carbohydrates (sugars) and lipids (fat). FGF23 also controlled phosphate metabolism.

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"We discovered that BP3 has a marked effect on metabolic regulation." "As the BP3 chaperone increases, the effect of FGF 19 and FGF 21 will also increase due to the increase in signal, "That's why it is a powerful" driver "of carbohydrate and phosphoric acid metabolism, so that as more taxis become available in New York, we can deliver everyone who needs to move," Mr. Wellstein I am talking.

In addition, Mr. Wellstein said, "As metabolism rises, fat in the blood and liver treated fats are converted to energy and can not be saved." "The work of FGF 21 is also to control fat breakdown, already The same can be said about the storage of some fat. "

Although the results of this research were excited by scientists, further research is required before investigating whether FGFBP 3 is equally effective in treating human metabolic disorders.