When using LSD What is the state of the brain?

The drug LSD developed almost 80 years ago was legally regulated as causing hallucinogenic symptoms and risk of abuse. However, recently attention is also gaining attention on positive effects, such as knowing that use of extremely small amounts has an effect of enhancing creativity, taking medicine at terminal medical care to be considered. When taking such LSD, what kind of change is occurring in the brain, movie "Your Brain on LSD and Acid"Explains it.

Your Brain on LSD and Acid - YouTube


The drug LSD also known as "ACID" is a drug known for being hallucinogenic.


When considering what the LSD will have on the body, the most important thing is the effect on the brain.


LSD was synthesized by Albert Hoffmann in 1938.


Hoffmann, who contained the synthesized LSD in his mouth, became a memorable man who first tripped at LSD.


However, the LSD used as a psychedelic therapy has spread to those seeking hallucinogenic effects after the 1960s, and in the latter half of the 1960s LSD sales were considered a crime and use in research applications was also regulated.


Whereas other drugs are taken in grams, LSD is taken in units of one ten thousand grams.


LSD is known to bind with dopamine receptors, adrenergic receptors, glutamate receptors and so on.


In addition to that, hallucinogenic symptoms are thought to occur by binding to the serotonin receptor "5H2TA" and inhibiting the action of serotonin.


And hallucinogenic symptoms are known to last longer than 12 hours.


In recent years, researches on LSD were resumed, the influence on the brain was investigated by a method using a brain image,Visual cortexIt is known that it acts on.


In the experiment that 20 volunteers take 75 micrograms of LSD for 2 weeks, the effect that optimism, sociability, creativity has risen has been reported.


LSD is also used for treatment. By taking it to the terminal patient ... ...


Reduce anxiety,Quality of lifeWe have also succeeded in improving quality of life (quality of life).


Take a small amount of LSDMicrodoseAnd the effect of increasing creativity has also been found.


LSD has no addictive nature, and it also knows that it is less dangerous than narcotics such as cocaine and heroin.


Nonetheless, it is certain that some people will cause hallucinations and panic symptoms by taking LSD.


Also, it is also known that after stopping taking LSD, a "flashback" phenomenon occurs that suddenly revives the sensation and perception of taking LSD.Hallucinogen persisting perception disorder (HPPD)Hallucinogenic symptoms such as never ending can occur.


It is proved that exaggeration is "to cause psychosis" or "to raise suicide rate" which is often thought of in LSD. And recent studies have begun to understand that LSD has a positive effect.