Research results will be announced that will make it possible to suppress the desire of alcoholism "I want to drink even more"


ByImagens Evangélicas

Currently, there are only hospital treatments for treating alcoholism as rehabilitation by refusing alcoholic beverages, but research results with the possibility of becoming a new treatment method have been announced by the National Institute of America Was

Translational Psychiatry - 11 [beta] -hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse
http://www.nature.com/tp/journal/v6/n3/full/tp201613a.html

A common drug for ulcers can prevent alcohol abuse | Ars Technica
http://arstechnica.com/science/2016/03/a-common-drug-for-ulcers-could-prevent-alcohol-abuse/

A joint research team of The Scripps Research Institute, the National Institute for Alcohol Abuse and Addiction Research, and researchers of the National Institute for Drug Abuse, has been investigating the molecular mechanism of alcoholism for many years . This time, the team is a kind of adrenocortical hormone and has a role to support the immune systemGlucocorticoidI focused on the substance. Previous studies have shown that the body of people who drink alcohol frequently can not regulate glucocorticoids properly and by suppressing the secretion of glucocorticoids it is said that "alcohol intake after alcohol ingestion It is known to reduce the desire to "want to want".

ByDavid Goehring

The joint research team had been researching drugs that allow glucocorticoids to be regulated and is extracted from Amakusa called LicoriceCarbenoxoloneDiscovered that it has an effect of suppressing the activation of enzymes that increase the effect of glucocorticoids. Briefly, taking carbenoxolone can reduce the secretion of glucocorticoids and reduce the desire for alcohol.

ByDaveblog

The joint research team carried out experiments to give carbenoxolone using alcohol-dependent mice and healthy mice, and the intake of alcohol decreased in both mice.

Dr. Pietro Sanna, the neuroscientist who conducted the experiment, said, "Since the responses of mice are not always the same as humans, we will do experiments for humans next time." However, since carbenoxolone is a substance already approved for human use, safety has been proved. What is not known is whether it has the effect of suppressing alcohol abuse. If humans can also recognize the same effect as mouse experiments, there is a possibility that new treatments for alcoholism will emerge.

in Science, Posted by darkhorse_log