How is sleep and mental health connected in the brain?
From various studies that adverse effects such as drowsiness and physical condition deteriorate from daytime when irregular life and sleep deprivation continueDiscoveredAlthough it is clear that sleep deprivation has deep connection with mental health in the brain, it is also related to mental disorders.
Why sleep could be the key to tackling mental illness
How sleep and mental health linked linked in the brain | World Economic Forum
Genetics of mental disordersBiochemistryThe basic principle is a field that has just started research but has not yet been clarified. The definition of the word "mental disorder" itself is ambiguous, and anxiety symptoms, depression, psychosis, etc. are gathered together. While the number of patients diagnosed with psychiatric disorders is increasing, investigating the causes of mental disorders and establishing therapeutic methods are important issues, but Professor Russell Foster, who is studying brain science at Oxford University, From the scientific basis of the scientific evidence, to treat mental disorders, we need to pay more attention to sleep. " According to Professor Foster, from various research results, it has been found that a state in which insufficient sleep is not obtained due to insomnia or the like is liable to cause a mental disorder, furthermore, by treating a sleep disorder, It will lead to prevention.
Until now, the effects of sleep tend to be neglected in the treatment of mental disorders, but in reality, how does sleep and mental health interlink in the brain? In order to understand the relationship between sleep and mental health, firstly sleep and sleepBiological clock(Circadian rhythm) that you need to know about the mechanism. The body clock has not only the function of informing the approximate time of the day but also the function of adjusting the cell so that it works at an appropriate time and place. Also, you must switch through thousands of genes in order and at the same time. Substances such as protein, encytos, fat and hormones are absorbed in the body, decomposed, changed by substance metabolism, play an important role in processes such as growth / regeneration / metabolism / cell repair.
The biological clock, which coordinates these functions, can be applied to the genome of all organismsBuilt inis. In the case of humans, physiological functions are composed mainly of "activity time" and "sleeping time". The time during which human beings are consuming a lot of energy, consumes food and moisture, and internal organs perform digestive activities to take in nutrition. Meanwhile, during sleep, energy consumption and digestive function are deteriorated, activities essential for human beings to live, such as repair of cells, removal of toxins, memory organization and information processing in the brain, are performed in the body.
However, if the life rhythm goes wrong due to jet lag, irregular working hours, mental disorder, etc., the biological clock will be displaced. When the biological clock is disturbed, it becomes difficult to control emotions, becomes angry, problems of cognitive function deteriorate memory and concentration, suddenly get sleepy in health, become sensitive to pain and cold Influence such as becoming susceptible to cancer and diabetes occurs.
It was the first time in the late nineteenth century that the relationship between the three, "psychiatric disorder" "displacement of the body clock" and "lack of sleep" was pointed out, a German psychiatristEmile KreperinAnnounced. Today, about 80% of patients with schizophrenia have sleep disorders and disorders of the body clockWatchedIt is listed as one of the features of schizophrenia, but sleep disorder lastsNeglectIt is a symptom that has been taken as a reason for social isolation or unemployment or as a side effect of psychotropic medicine.
However, Professor Foster led Oxford University's Sleep & Circadian Neuroscience Institute (SCNi), Sleep disorders and disorders of the body clock are the same neuropsychiatric transmission pathway in the brain as in the mental disorder, because schizophrenia patients complaining of sleep disturbance claim to stop taking psychotropic drugs I guess you are sharing. Professor Foster says, "The system of sleep and biological clocks was born as a result of complicated interactions between neurotransmitters and hormones at various parts of the brain, ie abnormalities in one of the neurotransmission systems in the brain In the same way, mental disorder also occurs due to abnormality in the neurotransmission system in the brain, sleep disorder and wrong body clock occur simultaneously, "he said, He argues that it is not surprising that sleep disorder and mental disorder occur simultaneously, or disorder of the body clock worsens mental disorders.
According to Professor Foster, most of the health problems caused by sleep disorders are common as symptoms of mental disorders, but the relation with sleep deprivation is almost neglected, On the other hand, it has been found that many genes play a critical role in both sleep disorder and psychiatric disorder. Sleep anomalies such as insomnia and sleep apnea syndrome have been distinguished as diseases other than mental disorders but schizophrenia of depression and childhood onset is necessary for clinical diagnosis as initial symptoms It has also been found that sleep disturbance tends to occur before symptoms. For the above reasons, Professor Foster points out the possibility that sleep and disturbance of life rhythm is an important factor in the early diagnosis of mental disorders, and that early detection of sleep disorders may be useful in treating mental disorders.
Also, Professor Foster went with a psychologist at the University of Oxfordthe studyThen, patients with schizophrenia suffering from paranoia suffering "Cognitive behavioral therapy"He said that the quality of sleep improved, the delusion decreased, and the anxiety and depressive symptoms improved as well. In other words, Professor Foster speculates that by treating sleep disorders it is also effective for symptoms of mental disorders.
Because sleep disorders can cause not only the simple problem of "sleep at night" but also serious health problems, Professor Foster has clarified the cause of sleep deprivation, received cognitive behavioral treatment, I insist that it is important to get enough of sunlight and get appropriate medication. Professor Foster says, "It is time to learn the importance of sleeping in society as a whole, sleep is very important especially in mental disorders. By correcting sleep disorders, health problems including mental disorders can be improved to improve the quality of life I will be able to improve not only the patient but also the quality of life of nursing partners. "
in Science, Posted by darkhorse_log