Chronic sleep deprivation reduces immune function, what is the optimal sleep time?


By

Dave Young

It is known that if sleep deprivation continues, the plasticity of the brain changes, affecting memory andcausing memory loss, which has an adverse effect on health. It has been demonstrated that if it continues, the function of the immune system will decline.

Transcriptional Signatures of Sleep Duration Discordance in Monozygotic Twins | Sleep | Oxford Academic
https://academic.oup.com//sleep/article/doi/10.1093/sleep/zsw019/2952682/Transcriptional-Signatures-of-Sleep-Duration



Chronic sleep deprivation suppresses immune system: Study one of first conducted outside of sleep lab --ScienceDaily
https://www.sciencedaily.com/releases/2017/01/170127113010.htm

As there is data that Japan is the most sleepless country in the world, many people should spend their days without getting enough sleep. Continued lack of sleep can make you feel sluggish or ill, but research conducted at the UW Medicine Sleep Center at Harbor View Medical Center scientifically explains the mechanism by which physical upset occurs during lack of sleep. doing.

It is known that 31% to 55% of human sleep time is affected by genes, and the remaining factors are determined by behavior and environment. Therefore, the research team took blood samples from 11 pairs of identical twins to see how they differ in the blood of twins with different sleep cycles. According to researchers, by looking at the blood of identical twins with similar heritability, it is possible to investigate the effects of sleep deprivation other than genetic factors.

Existing data from the laboratory environment have shown that reducing sleep time activates immune cells and improves inflammatory markers, but the research team found that long-term sleep deprivation in the natural environment. I paid attention to the influence of. As a result of the investigation, it was confirmed that one of the twins who actually spends a short sleep time every day has stopped some activities related to the immune response of white blood cells. This is the first study to show a decline in immune function due to chronic sleep deprivation.

Dr. Sina Galib, one of the study authors and head of the UW Medicine Sleep Center, said, 'The results of this study show that when a vaccine is given to people who are sleep deprived, the antibody response is reduced, and people who are sleep deprived. This is consistent with some studies showing that people are more likely to get infected if they are exposed to the 'Rhinovirus, ' which is the cause of colds. '

According to a study by the Centers for Disease Control and Prevention, the average sleep time of Americans has decreased by 1.5 to 2 hours in the last 100 years, and about one-third of the working population sleeps 6 hours every day. It is known to be less than. Dr. Nataniel Watson, co-head of the UW Medicine Sleep Center, said, 'We show that if you get enough sleep, your immune system works best. To maintain optimal health, every day. It is recommended that you sleep at least 7 hours. '


By Patrick Brosset

in Science, Posted by darkhorse_log