Potential for female ovaries to produce new eggs

ByMulan

Dogma is that the number of eggs in a woman's ovary is constant and does not increase over its lifetime, but evidence of the formation of a new ovum from a specimen of the ovary of a patient who was undergoing a specific medication treatment It has been shown that it may be a treatment for elderly childbirth and female infertility.

Evidence suggests women's ovaries can grow new eggs | Science | The Guardian
https://www.theguardian.com/science/2016/oct/07/evidence-suggests-womens-ovaries-can-grow-new-eggs

ResearchHodgkin's lymphomaWhich is a treatment forABVD therapy"Eleven patients undergoing medication called" OEPA-COPDAC ", a therapeutic drug with the possibility of causing infertility in addition to ABVD therapy, were used among three of them was doing.

Comparison of ovarian specimens of these ABVD therapy patients with ovarian specimens of 10 healthy women showed that the density of eggs from 3 patients who used OEPA - COPDAC in combination was much lower than that of healthy females On the other hand, from ovarian specimens of patients who received only ABVD therapy, the density of ova two to four times higher than healthy women was confirmed.


Professor Evelyn Telffer of the University of Edinburgh, who led the research, said, "The density of ova between 2 times and 4 times normal is unexplainable except that a new egg is produced." If this finding can be reproduced, it will overturn the existing concept of "the number of female ova is constant", and it is pointed out that there is a possibility that it can be applied to various treatment methods.

However, these findings are entirely unexpected for the research team, and it is not clear whether ovum cells which are considered to be increased are functional, how to reproduce it, and the mechanism have not been elucidated, and Professor Telffer We will continue to investigate how ABVD therapy worked. " On the other hand, we are also giving warnings to infertility treatment clinics aggressive in several new therapies so as not to be provided as "new fertility treatment" until the basic science is elucidated.

About this discovery, David Albertini, Director of the Center for Human Reproduction (CHR), who provides egg donors and research on infertility / in vitro fertilization, said, "Originally eggs were stimulated by treatment and surfaced," "The eggs that were scheduled to divide have been stimulated and divided into two or more" and skeptical view that various possibilities are considered, and additional investigation is necessary until the research is reproduced I pointed out.

ByWill House